Casey Greene

Casey’s lab at the University of Pennsylvania is dedicated to developing computational tools that biologists use to gain insights from other labs’ data as easily as from their own.

More than 2 billion dollars’ worth of publicly funded genomics data are freely downloadable. These data represent a rich and underused resource, but they are hard to use because the data are comprised of many different experiments.

Standard algorithms struggle with these “messy” datasets. Casey’s lab develops computational techniques that are robust enough to analyze and interpret this public resource. These algorithms have applications across many disease areas and, perhaps most importantly, to questions of basic biology.